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Storage management methods for chemical reagents
2024-08-06
The storage of chemical reagents is a daily task for laboratory personnel, requiring management personnel to have a high level of knowledge of chemical reagents. General chemical reagents are stored separately according to their elemental, inorganic, organic, indicator, etc.
Inorganic and organic substances should be stored separately according to the types and specifications of reagents. Due to the wide variety of types and specifications, they will not be elaborated here. For some infrequently used reagents, management personnel should conduct regular inspections to ensure that the reagent packaging is intact, the labels are complete, and the handwriting is clear. Solid reagents should have no hygroscopicity or deliquescence; Liquid reagents should have no sediment, otherwise, the sealing condition of the reagent should be checked. Some reagents require special and careful inspection, such as oil seals on potassium and sodium surfaces, and water seals on white phosphorus and mercury surfaces to ensure compliance with requirements and avoid potential hazards. The quality of chemical reagents is one of the factors that directly affect the quality of experiments, and management personnel should have certain knowledge of reagent quality judgment.
The remaining reagents after opening are generally prone to spoilage, including: 1. Changes in the shape and state of the reagents, such as sodium hydroxide changing from crystals to powder. 2. Changes in the volume of reagents, including volatilization and sublimation, such as a decrease in the amount of reagents in iodine containing bottles, and discoloration and opacity of the bottles. 3. Changes in color, such as discoloration of test strips after long-term storage, precipitation of mercuric chloride (HgCl2) and silver nitrate (AgNO3) solutions; White precipitate appears in tin dichloride (SnCl2) solution and brown color appears in ferrous sulfate (FeSO4) solution.
If the above phenomena occur in the reagent, it can be judged that the reagent has evaporated or deteriorated.
There are many reasons for reagent deterioration, and different reagents have different reasons for deterioration, which cannot be generalized. The sealing, exposure to light, moisture, and temperature rise of reagents may cause them to deteriorate. Some reagents, although well sealed, are prone to volatilization and deterioration (such as ether, carbon disulfide, tetrahydrofuran, isopropyl ether, etc.). The labels of these reagents should indicate the production date and shelf life, and management personnel should regularly check them.
There are various types of indicators used in chemical reagents, and generally solid indicators (except for test strips) are not easily spoiled even after long-term storage. In addition, some complex indicators may undergo polymerization or oxidation reactions when stored for a long time, resulting in turbidity or flocculent precipitation, which makes it difficult to accurately indicate the endpoint of titration. The indicator is used frequently, but the amount used each time is very small, and the total amount used is also small. It should be purchased, stored, and prepared as little as possible.
Classification and management of hazardous reagents
In the work of a chemical laboratory, it is necessary to come into contact with various chemical reagents, samples, and gases, volatiles, smoke, and other substances generated during chemical reactions. Some of these substances are toxic to the human body, some are highly corrosive, and some are flammable and explosive. In addition to strengthening safety education for students during the experiment, it is undoubtedly one of the necessary conditions for the experiment management personnel to have solid knowledge of safety management and reagent management.
The hazardous reagents used in chemical laboratories mainly include three categories: highly toxic substances, highly corrosive substances, and flammable and explosive substances. The following will explain the classification and management of hazardous reagents:
1. Highly toxic substances
According to the national standard GB6944-86, the drugs used in the laboratory include mercury salts, chromium salts, lead salts, arsenic compounds, nitrite compounds, polycyclic aromatic hydrocarbons and their derivatives, and organic compounds containing chlorine and phosphorus. Due to the wide variety and extremely complex types of poisoning, we will not describe them one by one here. Drugs (especially highly toxic substances) should be stored in separate cabinets, strictly managed, regularly checked and inventoried, and strictly prohibited from leaking out according to regulations. Some of these highly toxic substances, such as cyanide used in coordination titration, should strictly follow the "five double system" according to regulations, which includes two person custody, two person receiving and sending, two person receiving, double account, and double lock management. The reagent room for toxic substances should be well ventilated to prevent the accumulation of volatile and decomposed toxic gases indoors; Reagent bottles containing drugs should be well sealed and handled with care when moving to prevent contact between people and drugs.
2. Strongly corrosive products
The strong corrosive substances used in the laboratory mainly include concentrated sulfuric acid, hydrofluoric acid, liquid chlorine, liquid bromine, and other substances. When handling such materials, they should be handled with care, and collisions, falls, and strong vibrations are strictly prohibited. Shoulder carrying and carrying are also strictly prohibited. Highly corrosive products must be placed in a sturdy reagent cabinet and should not be placed in difficult to access locations such as the top or inner layer. Like other hazardous materials, strong corrosive substances must also be managed safely, used safely, and prevented from leaking out.
3. Flammable and explosive materials
There are various types of flammable and explosive materials used in the laboratory. Gaseous gases include hydrogen, coal gas, liquefied gas, oxygen, etc. Many flammable liquids have low flash points, are easy to ignite, have high volatility, low viscosity, low density, and are easy to diffuse. When they are used as organic solvents, their vapors can form gaseous explosives when mixed with air in a certain proportion. When this mixture encounters open flames, static electricity, or electric sparks, it can cause explosions. Therefore, laboratories often regard flammable liquids as the focus of fire and explosion prevention.
The petroleum ether, gasoline, and other substances used in the laboratory are the most flammable liquids. These substances can explode when in contact with strong oxidants such as nitrate, potassium permanganate, and potassium chlorate due to friction, collision, etc. It is important to take precautions.
Solid flammable materials include white phosphorus, metallic potassium, sodium, magnesium, aluminum powder, sulfur, and numerous inorganic and organic compounds. Some of these substances have spontaneous combustion, and many are extremely sensitive to heat, friction, and collision. The combustion of most flammable materials releases toxic gases.
Laboratory management personnel should be familiar with the properties, procurement, use, and storage knowledge of such reagents, and be well prepared for safety and fire protection. They should be vigilant and vigilant to prevent potential hazards of major accidents. The hazardous materials in the laboratory also include radioactive reagents and certain biochemical reagents, which are not commonly used in general laboratories and will not be described one by one here.
Chemical reagent management is a professional and complex discipline, and its procurement, handling, storage, and requisition should be managed by personnel with professional knowledge or guided on-site. The reagent room for storing hazardous materials should have clear warning signs and unrelated personnel are strictly prohibited from entering to ensure the safety of the laboratory. There are many types of chemical drugs and reagent solutions in the laboratory for the management of various chemical drugs. Most chemical drugs have certain toxicity and danger. Strengthening their management is not only necessary to ensure the quality of analytical data, but also to ensure safety. The laboratory should only store a small amount of drugs that need to be used in the short term. Chemical drugs are recommended to be stored in categories of inorganic substances, organic substances, and biological culture agents. Inorganic substances should be stored in categories of acid, alkali, and salt, while salts should be stored in order of metal activity. Biological culture agents should be stored in categories of different bacterial communities. Among them, highly toxic drugs that belong to hazardous chemical drugs should be locked in a dedicated drug cabinet and stored by a dedicated person. A system of application, approval, and dual person registration and signature should be implemented for use.
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